Post-Doctoral Scientist

Post-Doctoral Scientist

Contract: 12 months (with potential extension)

Salary: £21.22 - £26.52 per hour (based on experience)

Location: Bracknell (Hybrid options available)

CPL are partnering with a large pharmaceutical company to recruit for a Post-Doctoral Scientist to advance antibody-drug conjugates (ADC) from lab to real-world application using mechanistic PKPD, systems pharmacology, and pharmacometrics.

Key Responsibilities:

• Develop a Clinical Utility Index for ADC PKPD and Exposure-Response modeling.

• Determine optimal dosing and regimen for better therapeutic index.

• Create cellular mathematical models for ADC components.

• Assess therapeutic index by evaluating affinity and half-life.

• Potentially expand to other conjugates like siRNA and Radioimmuno conjugates.

Qualifications:

• PhD in Pharmacometrics, Pharmaceutical/Biomedical Sciences, Computational Sciences, Engineering, or related fields.

Preferred Skills:

• Proficiency in software like R, Monolix, NONMEM, MATLAB.

• Experience in QSP, PK/PD, exposure-response modeling.

• Strong communication and presentation skills with a solid publication record.

• Excellent data analysis and reporting abilities.

• Self-motivated and eager to learn new techniques.

• Understanding of pharmacokinetics and pharmacodynamics principles.